The 2 main characters are hormonal teenage boys (especially Chad), so several episodes and parts of episodes involve them trying to impress or go out with girls their age. Halfway through, Chris stops and rarely does this, unlike Chad. Most episodes are fairly subtle with their suggestive content and references. Almost all of them could as well appear on Cartoon Network. Some kissing and hugging occurs at times. Chris' mother's boyfriend appears in his underwear in some scenes, but not in a sexual content.
There are a few exceptions, such as a brief scene in episode one where Chad's father is being slapped by a woman while he and his partner are in their underwear. A dildo and a BDSM mouth gag are seen in the bottom right corner of the screen. In the same episode, Chris tells his teacher to "put his dick in a pencil sharpener and spin it". In episode 5, Chris asks, "why do girls like dicks?" (he is talking about unlikeable guys, but it's meant to sound like he's talking about genitalia). A man is nude in a scene from that episode, and is shown full frontal, but for some reason, he has no genitals. In episode 7, Chris takes sex aid pills to help Chad impress a girl he knows (and fails horribly).
Episode 2 is the most sexual episode in the show, and it revolves around Chris and Chad trying to see female nudity so that Chad can get over his fear of the female body. Sexual content here includes: an anatomy of the vagina, a TV which displays scrambled pornography (it is extremely fuzzy and impossible to actually see, but moaning and porno music is heard), porno magazines shown at both the beginning and end with women posing, but with no nudity, a boy talking about a porn shoot with vivid descriptions, a strip club scene where an obese stripper dances for a couple of seconds with mildly revealing clothes, until she takes off her top (her breasts are barely visible), and a teenager imagining a naked woman in a night's sky made out of stars (she has large, visible breasts, but her genitals aren't visible).