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A survivor of a global pandemic is chosen as a perfect candidate to be sent by scientists into the past and the future in their attempt to track down Patient Zero, neutralize them, and change the future of humanity. Selected for her strong mental imagination, the insistent pull of an image from her forgotten past leads her to re-live her own past. Shot primarily in stills as in Chris Marker's photo-roman, ZERO features music performed by noted counter tenor Derek Lee Ragin, the voice of Farinelli.