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The last decades of the life of the now world-renowned painter Karel Purkyne and his struggle for the possibility of creative expression. After studying in Paris, he returned to Prague. He is not recognized, has no success and actually lives on the support of his father, the famous physiologist Jan Evangelista Purkyne. He finds his only understanding in his admirer Marie, whom he marries. But he loses her too because of his emotional attraction to another woman.