In the opening of the film, a Hippopotamus construction worker is shown urinating and his genitals are briefly shown.
The cartoon nudity is not very graphic but still looks like nudity.
One of the characters have big breasts and their nipples are visible through their clothing.
There is some sexual dialogue.
Fritz tricks three females (two cats and a kangaroo) into having an orgy in a bathtub, soon more people join it. A nude bunny holds his penis, and he urinates on a pig. An aardvark has sex with one of the bunny girls. A bunny girl tries to seduce a pig cop by jiggling her breasts and spreading her legs to reveal her vulva. One of the more graphic sexual sequences.
In two fantasy sequence, Fritz runs through a tunnel of breasts. He has sex with a topless woman.
Fritz has sex with a crow. Fritz's genitals are visible and the crow's breasts, butt, and vulva are also visible. This is the most explicit sexual content in the film which lasts for less than 5 minutes.
A sign says "ALL AMERICAN BOOTS!" and it shows a topless African-American woman depicted in 'blackface'. (this is the Robert Crumb's character Angelfood McSpade)
We see a topless horse. When she bends over or walks, we see her butt.
A lizard's breast pops out of her shirt.
A horse is raped by her heroin addicted rabbit boyfriend and two other characters after being violently beaten with a chain. The rape is not shown but she is seen afterwards, naked and traumatized.
The movie comes to a close with Fritz once again having sex with the three women from before in the hospital, this time in mid-air.