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When some shrimp from Colombia, tainted with cholera, is served to some people on a plane bound for L.A., an outbreak ensues. And a doctor sets out to find the source and contain it before it turns into a epidemic. And if things weren't bad enough, a drug smuggler who was carrying some drugs on him contaminates the drugs and are sold on the street. And to top things off, the doctor's husband who is on a camping trip with their two children is sick but did not show any symptoms until they were isolated from the rest of the world. Can she get to them in time?