Will & Grace (1998)

Gay lawyer Will Truman (Eric McCormack) and straight interior designer Grace Adler (Debra Messing) are best friends living in New York City. Grace is engaged to a real jerk until the relationship falls apart and she moves in with Will. It's supposed to be temporary, until Grace finds her own place, but more and more it looks like a permanent arrangement. Grace's secretary and assistant is fun-loving wealthy socialite Karen Walker (Megan Mullally); Jack McFarland (Sean Hayes) is Will's flamboyant gay friend.