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In present day East London, Will Kane is a med. school drop out, and existential loner whose hate of the system has led him to drifting into low and high line crime capers, with best bud Ricky Hammond in tow. With action in short supply, they agree to take a mule job from reliable French connection Pierre, who is doing small drug jobs for two East-End gangsters, who also happen to be local rivals: Tudor Barro and Willie C.. When Pierre dies, due to overeating for a mule job he was about to perform (67 packets of condoms filled with heroin), Will and Ricky recover the drugs through grizzly means which involve a knife, and some crude medical know-how. With London big-wig Willie C., also an old friend of Will's, suspecting that they killed Pierre in order to pilfer the drugs, all hell breaks loose. With tragedy, soul searching, old loves reacquainted, and a hail of bullets, this is an asphalt jungle cataclysm that few will forget!