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A funeral for one becomes a deathtrap for many when five old friend are held hostage at a remote summer home infested with killer flies. A tragic death brings the old gang to their hometown and they decide to spend the weekend at the vacation getaway from their childhood. What they don't know is that the home is host to a strain of mutant flies that feed on human flesh. One by one, the flies claim their victims, inhabiting their bodies and laying more of the deadly creature's eggs - and no one is getting out alive.