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Prior to his retirement in November 2011, Doctor Horowitz practiced otolaryngology at the Advocate Health Center in Chicago's Beverly neighborhood. He was graduated as a medical doctor by Jefferson Medical College in Philadelphia, Pennsylvania, in 1975. The following year he completed an internship at Philadelphia's Hahnemann University Hospital. He then moved to Chicago for a three-year residency program in otolaryngology at the University of Illinois Hospital. Through his practice on the south side of Chicago, Doctor Horowitz met Matt Liston, who later cast him as the doctor in Chasing October (2007).