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In a deprived area of England's industrial north, a young mother is hit by a forklift truck at work and loses her leg. Based on the true story of Lisa Ramos, Amputee follows the first year of mental and physical recovery from a limb amputation. The consequences for Lisa's mental health, her family and her relationship with her son are far more severe than the physical loss of a limb. Amputee is the story of one family's struggle to adjust to a new reality, told from the perspective of those who are brought closer together and those who get left behind.