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It is the year 2027, eight years after the first outbreak of The Sickness, a highly contagious, adaptive, and lethal virus. The world is now run by a pharmaceutical corporation called The Company, which distributes a treatment for the virus but charges a high price for it, putting the majority of people in a state of poverty and dependence. David Oscar is done fighting. He has lost all hope and hides in a small illegal clinic. David is a former member of The Flux, a rebel movement depicted as a terrorist organization in the media. The Flux believes The Company itself is responsible for The Sickness. After years of hiding from his past, David is found by members of The Flux, who persuade him to take part in an important mission that they believe will lead to a cure for The Sickness. What they discover when they break into a secure facility of The Company, is not the cure for The Sickness, but a young girl named Molly who has been held captive and subjected to Company experiments for years. As David and his companions help Molly escape the Company facility, the mutation inside her body manifests itself and the Flux members find out why she has been kept under lock and key for years.