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The Egyptian vampire lady Miriam (Catherine Deneuve) subsists upon the blood of her lovers. In return, the guys or girls don't age until Miriam has had enough of them. Unfortunately that's currently the case with John (David Bowie), so his life expectancy is less than 24 hours. Desperately he seeks help from, the famous, Dr. Sarah Roberts (Susan Sarandon). She doesn't really believe his story, but becomes curious and contacts Miriam . . . and gets caught in her spell, too.