Hammer and Sickle (1994)

This is an interesting yet bizarre little tale of a fictional experiment performed during the Stalin-controlled years in the USSR. The main character is changed from a woman into a man. This is part of a larger plan to change more women into men and have a stronger work-force/army, etc. It's a very in-depth character study of the main character, who tries to fit into a world that she (now 'he') doesn't really understand, especially since she's now a man - Stalin dislikes the results of the experiments and has the scientist killed. The main character then goes off to live a life as a simple, unknown everyday Soviet, but is inexplicably drawn into larger and larger schemes (somewhat reminiscent of "Forrest Gump" in that way). (s)He has run-ins with different important characters, including his ex-boyfriend from his days of being a woman, as well as going on a demented quest for the nurse with whom he possibly fell in love after the operation - However, he is trapped in his life as an important Soviet married man, and in the end makes a huge sacrifice for his country (unwillingly), and the movie goes from there to an ending that is possibly happy, yet still somehow incredibly depressing.