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Two friends, Luv (Vir Das) and Hardik (Kunal Khemu) are going through bad times. Luv has learned that his girlfriend has been cheating on him and Hardik is this close to being fired from his job. They both badly need a break and when their roommate Bunny (Anand Tiwari) informs them that he is going to Goa for a presentation, they jump at the chance for a vacation. Once in Goa, Luv meets a girl, Luna (Pooja Gupta) who invites him to a rave party organized by Russian mafia on a remote island. At the party, an experimental drug is introduced. Then, come morning, things go totally wrong for the three hapless guys and the girl. As it turns out, the untested drug has a deadly side effect...